Hypothesis 2: Skeletal and Joint abnormalities due to improper nutritional requirements 

Improper nutrition can be the precursor to many problems in large breed growing 
dogs.  Skeletal and joint deformities can happen as a consequence of over or under 
feeding which upsets the balance of particular nutrients.  In this case we are presented 
with a nine month old Rottweiler that is allowed free choice Large Breed food. This can 
lead to excessive caloric intake if the dog overeats. This results in an increased 
metabolism leading to developmental bone defects and eventually to increased cartilage 
proliferation.  Endochondral ossifications occur due to rapidly growing bones that 
become weak and less dense.  Immature growth plate closure can also occur.  Abnormal 
cartilage development, such as slow maturity and proliferation, accompanies abberations 
in ossification. The abnormalities described above all contribute to detectable skeletal 
disorders and accompanying joint problems.  The animal in our case shows symptoms of 
abnormal skeletal development and joint pain such as reluctance to climb stairs, 
discomfort when sitting, etc.  These symptoms may be linked to the animalŐs nutritional 
requirements not being met.