Hypothesis 3: Infection/ Inflammation TitanŐs physical findings may be related to an infection that has lead to an inflammatory response in the joint. This theory is supported by a previous trauma. He fell off the bed, and also he plays regularly with the other household dog. Playing may have lead to a penetrating bit or scratch wound that allowed for the introduction of bacteria. The previous trauma may have predisposed him to develop septic arthritis in one or more of his synovial joints. Another predisposing factor is the fact that Titan has allergies. Allergies often lead to skin infections which may result in the introduction of bacteria to the bloodstream. Common aerobic bacteria include staphlococcus, streptococcus, coliforms, and pasterella. Common anaerobic bacteria include fusobacterium, bacteroides, and peptostreptococcus. Fungi may also be a source of infection in to a wound. Titan is also experiencing a Grade III/VI non-weight bearing lameness. This is a common historical finding with infected joints. Bacterial infection often causes pain, swelling, and inflammation in the joints; commonly the stifle joint.