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This Concept Map, created with IHMC CmapTools, has information related to: PKU, Mattie Fenway should adopt diet without phenylalanine, elevated phenylalanine may develop epilepsy, Phenylalanine lack of PAH activity leads to serum phenylalanine 500micromoles/L, Mattie Fenway diagnostic test serum phenylalanine 500micromoles/L, Mattie Fenway presents with pregnancy, Tyrosine precursor for Thyroid Hormones, pregnancy involves fetus, fetus becomes child/adult, childhood history of PKU is autosomal recessive disease, serum phenylalanine 500micromoles/L saturates LNAA transporter into BBB, diet without phenylalanine to lower serum phenylalanine 500micromoles/L, child/adult becomes pregnant, childhood history of PKU involves mutation in PAH, Tyrosine precursor for catecholamines, diet without phenylalanine prior to next pregnancy, pregnant if exposed to elevated phenylalanine, child/adult if exposed to elevated phenylalanine, BH4 is cofactor for PAH, elevated phenylalanine may develop eczema, elevated phenylalanine may develop light pigmentation