Route of Delivery Because this patient has a high output fistula (700 cc/day), I will choose TPN as the route of feeding. You really should not feed via the GIT when there is a high output fistula present- Total bowel rest is indicated to allow for the possibility of spontaneous closure, which if it is going to happen, will usually require at least 3 weeks. The fact that it is likely that we will need to have the patient be on total bowel rest for 3 weeks means that this will be a longer-term type of feeding, which makes it unwise to use a peripherally placed line. A central line is indicated, and will allow us to provide optimal nutrition without having to worry about the osmolarity issues associated with PPN. I will initiate TPN cautiously, with close monitoring of electrolytes and blood glucose, to allow the patient to adapt to the level of feeding gradually and to avoid the incidence of refeeding syndrome, given his compromised nutritional status. It is likely that the patient will be started on TPN the hospital and stabilized before being sent home on TPN. I will start him on continuous feeding until he is tolerating it well, and then depending upon planned date of discharge, will switch to a cyclic feeding that he will be on at home. A home nutrition support service will be arranged for followup post d/c.