work until it is reactivated.
This Concept Map, created with IHMC CmapTools, has information related to: RA&MS, Biphasic Response at TARGET TISSUES, cell attachment to endothelium transendothelial passage and migration facilitating ACUTE INFLAMMATION, Post-Partum 3-6 weeks manifests as <Estrogen <Progesterone <ACTH <Cortisol <DHEA, DHEAS, Chronic Inflammation manifesting as RHEUMATOID ARTHRITIS, Biphasic Response at physiologic levels Vasoprotective, inflamed joints of rheumatoid arthritis, osteoarthritis, thyroid gland of Hashimoto's involved in pathology of RHEUMATOID ARTHRITIS, ACUTE INFLAMMATION if not well regulated leads to Chronic Inflammation, STRESS e.g. injury, infection, surgery, fasting, fatigue, exertion, fear, anxiety, circadian drive activates HYPOTHALAMIC-PITUITARY-ADRENAL AXIS, >follicular phase delayed folliculogenesis anovulation e.g. Post-Partum 3-6 weeks, found in inflammatory sites and the cytoplasm of EC, macrophages, and fibroblasts causing degranulation of mast cells vasodilation increased vascular permeability, FSH LH stimulates ovaries to produce PROGESTERONE, glucocorticoids, e.g. cortisol inhibit FSH LH, Pregnancy by third trimester +Estrogen +Progesterone +Cortisol +NE +1,25 vitD3 +PMNs, monocytes +Lymphocytes, eosinophils +ACTH +PRL, 17 BETA ESTRADIOL has a Biphasic Response, ovary, endometrium, placenta involved in inflammatory phenomena ovulation, luteolysis, implantation, menstruation, 17 BETA ESTRADIOL stimulates Catecholamines, Vascular and Tissue Injury by reaction with other O2 species producing bactericidal toxins & tissue injury, TARGET TISSUES at physiologic levels + EC proliferation + tubular networks + EC adhesion molecular expression + IL-10 production + IgM and IgG production + Beta cells (humoral immunity), VASOENDOTHELIAL SYSTEM expresses ICAM-1 and 2, E-selectin, P-selectin, glucocorticoids, e.g. cortisol inhibits CRH (& AVP)