Subchondral Bone neoplasia below the cartilage of the femoral head Invasion of neoplastic osteophytes into articular cartilage causes disruption of cartilage integrity. This may lead to acute inflammation of the cartilage as it attempts to repair the insult The response in the joint to this inflammation results in pain and loss of function. The space occupying mass at the cranial portion of the femoral head of the right hind limb would cause pain during motion. This pain would cause the left limb to compensate and therefore becomes sore as well but not as severe as the primary lesion. During exercise the lesion abrades the articular surface causing increased inflammation and discomfort. The condition did not improve with Rimadyl therapy because the neoplasia itself causes pain upon motion while Rimadyl would only reduce inflammatory responses. The location of the neoplastic lesion does not interfere with the function of any nerves or muscles therefore no deficits were seen in these areas. Neoplasia can be spontaneous and would not need a traumatic incident to occur. Joint effusion has not yet occurred because the magnitude of the inflammatory response has not yet reached a level to cause effusion.