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sickness map, rare sickness increase is constrained by *not easy to differenciate natural causes from others *not easy to diagnostic them, on site study!! pros good proof of bad living conditions, rare sickness increase is specified by percentage of sick people, percentage of sick people leads to on site study!!, *not easy to differenciate natural causes from others *not easy to diagnostic them leads to on site study!!, on site study!! cons *time consuming *not updated frequently