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This Concept Map, created with IHMC CmapTools, has information related to: Chapter 5-5, autocrine signalling eg cell self-signalling, paracrine signalling eg signal close cells, EPO-R causes replication and differentiation of erythrocytes, gp55 activates EPO-R, signalling ex endocrine signalling, signalling ex paracrine signalling, PDGF stimulates mesenchymal cells, autocrine signalling ex Friend leukemia virus, v-sis protein activates PDGF-R, erythropoetin (EPO) activates EPO-R, PDGF-R binds to PDGF, endocrine signalling eg signal distant cells, gp55 which is very similar to erythropoetin (EPO), mesenchymal cells expresses PDGF-R, v-sis protein performs autocrine signalling, PDGF-R binds to v-sis protein, signalling ex autocrine signalling, PDGF has high sequence homology to v-sis protein, signalling ex PDGF-R, Friend leukemia virus creates a protein called gp55