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This Concept Map, created with IHMC CmapTools, has information related to: Section 7-6, CpG sequences as discussed in Section 12.5, chromosomal arms in colorectal tumors, polymerase chain reaction is used to determine sequence polymorphisms, LOH of chromosomal arms, genes that have large numbers of CpG sequences, LOH is used to find tumor suppressor genes, localization of tumor suppressor genes, restriction fragment length polymorphisms are used to determine localization, secondary independent mutations are more frequent in genes, polymerase chain reaction is used to map tumor suppressor genes