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This Concept Map, created with IHMC CmapTools, has information related to: Ch 6, B catenin translocation to the nucleus causes proliferation, signal transduction pathways have functions that are classified as changing concentration of a protein, phosphorylation caused by kinase (TK), integrins can activate kinase (TK), signal transduction pathways have functions that are classified as changing location, GEF for Ras, functional redundancy is apparent in pathways controling myc, integrins signal between cytoskeleton, 3 different forms transcribed and translated from 3 different genes, 3 different forms that can preferably lead to proliferation, Ras has 3 different forms, signal transduction pathways have a built in functional redundancy, signal transduction pathways have functions that are classified as intrinsic activity, Ras binds to adaptor proteins, integrins provide anchorage dependence, adaptor proteins eg SH2, signal transduction pathways are turned off by changing shape of receptor, intrinsic activity eg modification of molecules, Ras when constitutively active causes cancers, functional redundancy allows for one protein to compensate for another