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This Concept Map, created with IHMC CmapTools, has information related to: discussion, Proline create Cryptic Sites, PDGF-R contains an SH2 Domain, Signaling Pathways e.g. integrins, Cryptic Sites via Hydrophobicity, Ras can cause Anchorage-Independance, IEG's act as transcription factors for DEG's, Effectors to give Functional Redundancy, SH2 Domain binds p-Tyrosine, SH3 Domain activats Sos, integrins bind ECM, integrins can cause Anchorage-Independance, integrins are activated Dimers, Signaling Pathways contain many Effectors, Signaling Pathways make use of IEG's, integrins undergo outside-in signaling, Signaling Pathways e.g. PDGF-R, Ras activates PIP3, PDGF-R contains an SH3 Domain, Signaling Pathways e.g. Ras, SH3 Domain binds Proline