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This Concept Map, created with IHMC CmapTools, has information related to: Section 8.4, extracellular signals cause advances in cell cycle, cyclin-CDK complexes are regulated by CDK inhibitors, TGF-b controls progression of the cell cycle, p27kip1 is suppressed by Akt/PKB, Akt/PKB in human breast cancers, p27kip1 is imposed in a post-mitotic state