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This Concept Map, created with IHMC CmapTools, has information related to: chapter 11-5, heritable epigenetic alterations ex promoter methylation / demethylation, Darwinian evolution and tumor development eg genetic changes cause phenotypic changes, Darwinian evolution and tumor development does not account for heritable epigenetic alterations, Darwinian evolution and tumor development misrepresents the number of loci affected, Darwinian evolution and tumor development does not account for LOH