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This Concept Map, created with IHMC CmapTools, has information related to: Section 11-12, human tumors don't reveal the identities, transformation requires 5 intracellular pathways, identities of proteins, mammalian body size may be correlated to transformation, transformation can be achieved by blocking PP2A, malignancies as will be discussed in Chapter 14, human cells are constructed to be highly resistant to immortalization, genes that program malignancies, human cells are constructed to be highly resistant to transformation, proteins that program malignancies, human tumors confounds understanding of transformation, identities of genes, PP2A is heterotrimeric, immortalization can be achieved by blocking PP2A, PP2A in an extremely complex holoenzyme, genetics of human tumors