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This Concept Map, created with IHMC CmapTools, has information related to: Class discussion Chapter 9, Signaling pathways eg Protein kinase inhibitors, p53 did not follow model of LOH, SV40 by Immunoprecipitation, Uninfected by SV40, Tetramers still form but lack function with Mutation, p53 is a protein of 53 kD, p53 is a Transcription Factor, p53 inactivation can be Inherited, Tumors at different Ages, Siah degrades Beta-catenin, Apoptosis kills Mammary gland cells, Inducers in three known Signaling pathways, Mutation of p53, p53 was found in cells Infected, p53 was first studied in SV40, Transcription Factor level can be influenced by changing Modification, Infected by SV40, Apoptosis prevents Overproliferation, p53 leads to increase of 14-3-3sigma, Modification eg Phosphorylation