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This Concept Map, created with IHMC CmapTools, has information related to: 13.1, Tumor mass contains cells that are Neoplastic, Heterotypic Signaling involves signaling through Growth Inhibitory Factors, Stromal Cells e.g. Endothelial Cells, Endothelial Cells release PDGF, Pericytes release VEGF, Pericytes constitute Mural Cells, Heterotypic Signaling involves signaling through Trophic Factors, non-neoplastic e.g. Stromal Cells, Genetics could not account for Tissue, non-neoplastic epithelial tissues are formed from Interdependant cell types, Heterotypic Signaling effects the growth of Tumor Masses, Carcinomas have neoplastic Epithelial Cells, Heterotypic Signaling refutes Cell Autonomy, Tumor Masses e.g. Carcinomas, HB-EGF attracts Pericytes, ECM contains Proteoglycans, Proteoglycans can store Growth Factors, Heterotypic Signaling involves signaling through Growth Factors, ECM bind to cells through Hemidesmosomes, Tissue aka Tumor mass