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This Concept Map, created with IHMC CmapTools, has information related to: chapter 14-7, EGF mediated cell motility requires that cell surface proteases degrade ECM at leading edge, stress fibers eg regulate contraction of cytoplasm, Rho GTPases control cell adhesion, subfamilies of Rho proteins ex Rac, cell motility requires continuous reconstruciton of actin cytoskeleton, cell motility ex EGF mediated cell motility, subfamilies of Rho proteins ex Cdc42, subfamilies of Rho proteins ex Rho proper, Rho GTPases effects are different in each type of cells, filopodia eg spikelike structures enable advancing cell to explore territory before cell reaches it, EGF mediated cell motility is caused by filopodia, lamellopodia eg broad flat sheetlike protrusions from cell surface, cell motility is caused by motogenic factors, cell motility can be caused by HGF in epithelial cells, Rho GTPases help to create stress fibers, EGF mediated cell motility sometimes causes metastasis, Tiam1 activates Rho GTPases, Rho GTPases have lipid groups attached at C termini to anchor to intracellular membranes, Tiam1 causes localized polymerization of actin at leading edge of migrating cells, Rho GTPases control cell shape