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This Concept Map has information related to: Chapter 16 discussion, preclinical testing leads to clinical trials, hedgehog is an autocrine signal, experiment with Gleevec and pre-B lymphocytes no effect if Bcr-ABl plasmid, make mutants put themin viruses, proteosome inhiitor prevents degradation of unecessary bad protiens, Cancer treatments involve anti-cancer drugs, how druggable it is is dependent on ability to be inhibited by a low molecular weight compund, multiple therapies increase toxicity, Gleevac targets PDGF-R, antibody last longer in blood