WARNING:
JavaScript is turned OFF. None of the links on this concept map will
work until it is reactivated.
If you need help turning JavaScript On, click here.
This Concept Map, created with IHMC CmapTools, has information related to: Complement, Classical Pathway Triggered by Antibodies Part of Adaptive Immunity, Lectin Pathway Triggered by sugars on cell Part of Innate, Complement System Major Functions of all pathways Rid of Immune Complexes, T lymphocytes ???? T-cells can be either T cytotoxic or T helper cells., Complement System Major Functions of all pathways Inflammation due to fragments, APC's ???? Needed because T-cells can't recognize pathogens by themselves, Complement System Major Functions of all pathways Cell lysis, Classical Pathway Trigger- C1QRS 1.C4 & C2 cleave becomes C3 convertase 2. C3A & C3B become C5 convertase 3. 5 splits into A&B and triggers steps 6-9, Alternate Pathway Trigger:Structures on microbial surface Same as classical but goes straight to C3, Lectin Pathway Recognizes mannose (sugar) on cell: trigger Same as classical but starts at 4 & 2, Alternate Pathway ???? Innate, Complement System 3 Major Pathways Classical Pathway, Complement System 3 Major Pathways Lectin Pathway, Activated macrophages Role White blood cells that phagocytize and stimulate other immune cells to respond., Complement System Major Functions of all pathways Opsonization, Complement System 3 Major Pathways Alternate Pathway, Complement System Major Functions of all pathways Virus Neutralization