WARNING:
JavaScript is turned OFF. None of the links on this concept map will
work until it is reactivated.
If you need help turning JavaScript On, click here.
This Concept Map, created with IHMC CmapTools, has information related to: Inflammation, Rise in Blood Volume Causes Heat and Redness, Not all chemoattractants are chemokins Other Types Byproducts of complement C5a, C3a, Release Molecular Mediators that recruit + activate effector cells ???? Low Molecular Weight Regulatory Proteins, 1. Bacterium becomes attached to membrane evaginations called pseudopodia ???? 2. Bacterium become ingested, forming a phagosome, Vascular Permeability Causes Edema + Tissue Swelling, Vasodilation Causes Rise in Blood Volume, Integrin on the Neutrophil Membrane Binding of these to receptors on Neutrophils triggers Chemokines, Heat and Redness Within Hours Leukocytes adhere to endothelial cells in the inflammed region and pass through the walls of capillaries into the tissue (Extravasation), Integrin on the Neutrophil Membrane Binding of these to receptors on Neutrophils triggers Chemoattractants that cause cells to move twoards higher concentrations of the agent, Low Molecular Weight Regulatory Proteins AKA Cytokines, 2. Bacterium become ingested, forming a phagosome ???? 3. Phagosome fuses with lysosome, Phagocytose Pathogen ???? Phagocytosis, Intercellular Adhesion Molecules on the endothelium Which control Adhesion, Chemotaxis, and Activation of Leukocyte Traffic, Edema + Tissue Swelling Within Hours Leukocytes adhere to endothelial cells in the inflammed region and pass through the walls of capillaries into the tissue (Extravasation), Chemokines Also cause Leukocytes to move into tissue sites by inducing adherence to endothelium lining, Leukocytes adhere to endothelial cells in the inflammed region and pass through the walls of capillaries into the tissue (Extravasation) Leukocytes Then Release Molecular Mediators that recruit + activate effector cells, Cytokines A subgroup Chemokines, Not all chemoattractants are chemokins Other Types Various N-formal peptides produced by the breakdown of bacterial proteins during infection, Chemokines Act as Chemoattractants that cause cells to move twoards higher concentrations of the agent, Integrin on the Neutrophil Membrane Increasing its affinity for Intercellular Adhesion Molecules on the endothelium