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This Concept Map, created with IHMC CmapTools, has information related to: Neurotransmitters, AMPA causing ↑gNa+, ↑gCa2+, ↑cAMP, ↑PKA which leads to excitation; located in hippocampus, amygdala, and basal ganglia, ↑gCl- leading to inhibition, nicotinic tansduces signal to conduct increase Na+ increase K+, dopamine acts on G-protein-linked receptors, ligand-gated receptors such as nicotinic, increase Na+ increase K+ causing excitation, increased NT release, ligand-gated ion channels such as GABA B, decreased cAMP increased gK+ decreased gCa+ which leads to inhibition, roles in anxiety and depression, NMDA receptor causing ↑gNa+, ↑gCa2+, G-protein-linked such as 5-HT4, increased IP3 increased DAG decreased gK+ increased gCa++ which leads to excitation, widespread, role in antipsychotic action, karinate causing ↑gNa+, ↑gK+, metabotropic causing ↓ cAMP or ↑IP3, ↑DAG, ↓ cAMP ↑gK+, ↓gCa2+ leading to inhibition; decreases pain transmission, ligand-gated such as 5-HT3, G-protein-linked receptors such as D2, D3, D4, ↑gNa+, ↑gCa2+ leading to obligatory co-agonist for function of NMDA receptor, glycine acts on ligand-gated ion channels, ligand gated ion channels such as AMPA