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This Concept Map, created with IHMC CmapTools, has information related to: Asthma, Environmental Exposures can activate Eosinophils, hypertrophy of smooth muscle which express Asthma susceptibility gene ADAM33, Environmental Exposures examples include nicotine, Leukotriene receptor antagoists specific drugs include Monteleuklast, GM-CSF can induce activation of Eosinophils, T cells which secrete IL-4, Mast cells which secrete IL-5, Mast cells which secrete IL-4, Th1 response can mitigate a Th2 response, Pharmacological Agents specific classes include Beta-2 adrenergic receptor agonsits, Pharmacological Agents with targets that include Th2 response, toll-like receptors (TLRs) can be activated in Macrophages, 18 months old is when she experienced an upper respiratory infection, IL-10 induce IgG4, second hand exposure occuring prenatally can trigger basement membrane deposition, Broncioalveolar lavage containing inflammatory cells examples include T cells, Pharmacological Agents with targets that include Interferon gamma, IL-12 inhibits production of IL-5, TLR-9 recognizes unmethylated CpG DNA, IL-5 are associated with Th2 response