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This Concept Map, created with IHMC CmapTools, has information related to: 11.15 - Biochem - G6PD Deficiency (Darcy's Map), deletion located on q28 locus, becomes conjugated by binding to albumin when inhibited, contributes to total serum bilirubin 19 mg/dL (normal ə.9 mg/dL), Glucose-6-Phosphate Dehydrogenase when deficient, leads to decreased levels of NADPH, NADP+ as coenzyme/ electron acceptor, biochemical reductant for the body's biosynthetic (anabolic) pathways, increased intravascular hemolysis predominantly seen in acute hemolytic episodes, increased extravascular hemolysis contributing to total serum bilirubin 19 mg/dL (normal ə.9 mg/dL), anemia indicative of insufficient healthy RBC in blood, G6PD Deficiency consistent with symptoms, including reticulocyte count 262 x 10^9 /L, G6PD Deficiency consistent with symptoms, including total serum bilirubin 19 mg/dL (normal ə.9 mg/dL), decreased levels of reduced glutathione (GSH) affects normal maintenance of REDUCED STATES of SULFHYDRYL GROUPS in proteins (including hemoglobin), Pentose Phosphate Pathway consists of two irreversible oxidation reactions, glucose-6-phosphate dehydrogenated to 6-phosphogluconolactone, accumulation of hydrogen peroxidase which causes peroxidation of membrane lipids, Pentose Phosphate Pathway is the only source of NADPH for RBC, point mutation located on q28 locus, q28 locus is inherited via X-linked genetics, anemia stimulates production increased immature RBC count, attach to RBC membranes causing increased extravascular hemolysis, muscle glycogen synthase for muscle's energy storage