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This Concept Map, created with IHMC CmapTools, has information related to: jancsy NRS, pancreatic insufficiency (90-95% of CF pts) fats/fat soluble vitamins excreted in stool Rickets and Osteoporosis (vit D), pancreatic insufficiency (90-95% of CF pts) fats/fat soluble vitamins excreted in stool (vit E), pancreatic insufficiency (90-95% of CF pts) plugging of ductules and acini; reduced water content of secretions; precipitation of proteins autodigestion of pancreas, pancreatic insufficiency (90-95% of CF pts) deficiency in insulin hyperglycemia, pancreatic insufficiency (90-95% of CF pts) fats/fat soluble vitamins excreted in stool steatorrhea, malnoursihment, poor weight gain, and failure to thrive nutritional deficiencies delayed onset of puberty, pancreatic insufficiency (90-95% of CF pts) malabsorption of bile acids gallstones (15% of CF pts), pancreatic insufficiency (90-95% of CF pts) lack of trypsin meconium ileus in newborns (10% of CF newborns), malnoursihment, poor weight gain, and failure to thrive may lead to death, pancreatic insufficiency (90-95% of CF pts) abnormal mucin in gallbladderer gallstones (15% of CF pts), pancreatic insufficiency (90-95% of CF pts) fats/fat soluble vitamins excreted in stool increased bleeding (vit K), pancreatic insufficiency (90-95% of CF pts) fats/fat soluble vitamins excreted in stool malnoursihment, poor weight gain, and failure to thrive, pancreatic insufficiency (90-95% of CF pts) fats/fat soluble vitamins excreted in stool visual disturbances, dry skin (vit A), pancreatic insufficiency (90-95% of CF pts) Reduced bicarb secretion in stomach in response to secretin digestive enzymes cannot fucntion at optimal pH