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This Concept Map, created with IHMC CmapTools, has information related to: B6 FH, 10 YO Female had a MI, FFA stored in Adipose Cells, TAG converted to Glycerol, HMG CoA Reductace (rate limiting enzyme in C synthesis) synthesises Free Cholsterol, Chlosterol Esterase into Chlosterol, Liver produces Bile Acid, CETP to exchange CE and TAG, VLDL acted on by Lipoprotein Lipase (in the capalaries), Father with Heterozygous FH resulted in Homozygous FH, Cytokines contribute to Atherosclerotic Plaque, ACAT into CE, Mother with Heterozygous FH resulted in Homozygous FH, DNA codes for LDL Receptor Protein, VLDL use CETP, Endoplasmic Reticulum releases LDL Receptors (on almost all tissues), CE converted by Chlosterol Esterase, Apo E and Apo C2 becomes LDL Containing High Chlosterol, Apo E and C2 (added in circulation from HLD) makes VLDL, SREBP translates to nucleus and binds to SRE, Nacient VLDL obtains Apo E and C2 (added in circulation from HLD)