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This Concept Map, created with IHMC CmapTools, has information related to: T Cell Development, V,J,C regions recombined using RAG, MHC Class I (Alpha 1,2,3 Beta 1) transported to Cell Surface, T Cells formed from T Cell Precursors (in bone), CD4 Helper T Cell ataches to and matures MHC Class II (Alpha 1,2 Beta 1,2), Pathogen digested in Vessicle, V,J,D,C regions recombined using RAG, Negative Selection (if bind to dendrite, die) into Single Positive CD4 or CD8, T Cell Receptor (travels with CD3) on Niave T Cell, Peptide in ER, Macrophage phagocytoses Pathogen, ER with Phagolysosome, Notch 1 promotes Double Negative (No CD4 or CD8) Only CD2,5 Adhesions, CD8 Cytotoxic T Cell promotes Apoptosis of infected Cell, CD4 Helper T Cell promotes Release of Cytokines Phagocytosis of Pathogen, Double Negative (No CD4 or CD8) Only CD2,5 Adhesions first recombination of B, G, D into Double Negative, RAG creates diverse Complementaty Determining Region, ERAP attached to MHC Class I (Alpha 1,2,3 Beta 1), Phagolysosome modified with ERAP, Niave T Cell with CD8 Cytotoxic T Cell, Niave T Cell with CD4 Helper T Cell