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This Concept Map, created with IHMC CmapTools, has information related to: Celiac, Patient (14 year old male) presents with delayed puberty, Patient (14 year old male) presents with 15% in weight, delepmental levels including Tanner stage 2 (genitalia), proteins broken down b/c pancreas can still secrete enzymes, Patient (14 year old male) presents with social withdrawl, IBD (inflammatory bowel disease) including Crohn's, Patient (14 year old male) has labs, parietal cells in stomach secretes intrinsic factor, heme transporter then deposited in enterocytes, labs including CBC, previous extended bout of diarrhea allowed gliadin to move into lamina propria of small intestines, Patient (14 year old male) diagnosed with Celiac disease, sodium linked co-transporter then deposited in enterocytes, specific receptor in ileum then deposited in enterocytes, damage to ep. cells releases IL-15, gliadin is deamidated reacts with (on surface of APCs) HLA-DQ2, micelles then deposited in enterocytes, IL-15 activates intraepithelial lymphocytosis, enterocytes responsible for absorption, duodenal biopsy reveals villi atrophy