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This Concept Map, created with IHMC CmapTools, has information related to: Melanoma, Biopsy if cancerous Sentinel Node Surgery and adjuvant therapy, Factors Inherited p16 mutation, Melanoma Diagnosis High LDH, Interferon Side Effect Thyroiditis, Interferon Side Effect Autoimmunity, Autoimmunity These often indicate favorable outcome, Treatment Stage IV IL-2, Ipilumimab antibody agains CTLA-4, Vemurafinib B-Raf Mutation Drug Specifc TKI, ABCD if abnormal Biopsy, Interferon Mechanism Stimulates NK Cells and Macrophages Inhibits angiogenesis, Thyroiditis These often indicate favorable outcome, Factors Inherited Fair Skin, p16 mutation also associated w/ pacreatic cancer, Treatment Stage IV Vemurafinib, High LDH non-specific marker Biopsy, Treatment Stage I and Stage II Interferon, Melanoma Diagnosis ABCD, Treatment Stage I and Stage II Sentinel Node Surgery and adjuvant therapy, Interferon Side Effect Vitaligo