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This Concept Map, created with IHMC CmapTools, has information related to: Week 30, Andrik Doubek physical exam includes genital exam, testosterone inhibits hypothalamus, hypothalamus releases GnRH, cortisol inhibits anterior pituitary, 17α-hydroxyprogesterone level finding high 17α-hydroxyprogesterone, cortisol regulating negative feedback, 21α-hydroxylase deficiency causes lack of cortisol, serum hormone levels finding high androstenedione, at age 7 showing precocious pseudopuberty, leydig cells release testosterone, 17α-hydroxyprogesterone to androstenedione, gonadotrophin independant not central precocious puberty, HPG axis normal, so not central precocious puberty, free testosterone shows normal, 17α-hydroxyprogesterone converted to androstenedione, Andrik Doubek lab tests included Left-wrist/hand X-ray, 5 α-dihydrotestosterone binds to receptors, ACTH stimulation post value is 2500ng/dL, anterior pituitary part of HPG axis, inhibin B inhibits follicle stimulating hormone