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This Concept Map, created with IHMC CmapTools, has information related to: 1. Anticoagulant (All Combined - Mike), Death CV Cause -Cardiac tamponade, -Asystole (documented) -Heart Failure -Sudden Death -Non-CNS Systemic Embolism -Mycardial infarction -Stroke -Systemic Aterial Embolic event -Pulmonary Embolism -Other CV -Other Cardiac -Other, transfusion standard units -whole blood -pacakged RBC, Surgery prespecified CRF - Valve - CABG - PTCA - Cartoid endarterectomy - Peripheral Angioplasty - Limb amputation - Other, Safety Endpoint realized by Hepato-toxicity, Hepato-toxicity assessed by Liver Function Test, Visit has Type, MI qualified by Cardiac enzymes/markers of myocardial necrosis, Cardiac enzymes/markers of myocardial necrosis qualified by - Troponin release - Peak CK-MB - Peak CK, MI qualified by -ECG Changes -Symptoms, SEE embolous location -grafts -extremity -Mesenteric Artery -Spleen -Kidney -Retina -Other, Hospitalization Event has admission reasons CV, CV prespecified CRF - Angina (new) - A-Fib/Flutter - Cardiac Arrest (non-fatal), - Arrhythmia (Supraventricular) - Arrhythmia (ventricular), bleeding event has Symptomatic Bleeding in critical area - Peri-cardial - Intra-muscular - Intra-articular - Intra-ocular - Intra-spinal - Retro-peritoneal - Gastro-intestinal - Intra-cranial (intra-cerebral) - Intra-cranial (sub-dural), non-CV prespecified CRF - Cancer - Injury - Fracture - Psychiatric - Hematologic - Genito-urinary - Gastrointestinal - Diabetic Complication - Other, Efficacy Endpoint realized by MI, Stroke diagnostic type Uncertain, Death Other Vascular Cause -Peripheral Embolism -Aortic Dissection/rupture -CNS-Bleeding, FDA Endpoints for Anticoagulants qualified by Onset Date/time, -Recovery Status Assess Date -Rankin Scale (1-5) -Rankin Scale Modified (0-6) measures Global Disability, Stroke qualified by -Recovery Status Assess Date -Rankin Scale (1-5) -Rankin Scale Modified (0-6)