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This Concept Map, created with IHMC CmapTools, has information related to: Group A2 Case Jack Dawson, Psychotic episode identified by presence of Positive symptoms, Jack Dawson is a 25-year-old Caucasian male brought to the Emergency Department (ED) by the police after he was found running barefooted downtown dodging cars in subzero weather. presents with symptoms of Schizophrenia, DSM (Diagnostic and statistical manual) distorted perception of reality by having delusions, hallucinations, etc. Psychotic episode, Negative symptoms reduction in emotional expression Blunted affect, Dopamine pathways connects ventral tegmental area to prefrontal cortex Mesocortical pathway, Myxedema generalized nonpitting edema Hyperthyroidism, Dopamine pathways dopaminergic pathway for creating prolactin Tuberoinfundibular pathway, NMDA receptor antagonist of NMDA receptor PCP, Mesolimbic pathway dopamine pathway associated with positive symptoms Positive symptoms, Receptors glutamate receptor, dysfunction implicated in schizophrenia NMDA receptor, Extrapyramidal symptoms (EPS) neurodegenerative condition characterized by tremors, rigidity, bradykinesia, and postural instability Parkinsonism, Antipsychotic medications (atypical antipsychotic) D3 & D4 antagonists (& 5-HT2A) Olanzapine, Nigrostriatal pathway twitchy movement related symptoms from dopamine block Extrapyramidal symptoms (EPS), 5-HT2A receptor NT implicated in sleep, mood, depression and anxiety Serotonin, Dopamine pathways D2, D3, D4 Receptors, Diagnostic Studies checks for thyroid issues Thyroid Stimulating Hormone (TSH), Mesocortical pathway dopamine pathway associated with negative symptoms Negative symptoms, Receptors Dopaminergic D2 receptor, Jack Dawson is a 25-year-old Caucasian male brought to the Emergency Department (ED) by the police after he was found running barefooted downtown dodging cars in subzero weather. Pt. reports reports auditory hallucinations Positive symptoms, Glutamate excitatory neurotransmitte NMDA receptor