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This Concept Map, created with IHMC CmapTools, has information related to: Robert_Dillon_C3, T-cytotoxic cells (CTLs) CTLs are mature T-cells that underwent maturation in the thymus Thymus, Type IV hypersensitivity is a form of inflammation that is stimulated by Th1 cells and macrophages and is therefore... Cell-mediated, Antibody-mediated reaction leads to painless muscle weakness, diplopia and ptosis in Myasthenia Gravis, Robert Dillon, 28 y.o. Hispanic Male inflammation is mediating most of the symptoms of Robert Dillon inflammation, MHC Molecule MHC Class I molecules are MHC molecules composed of an alpha chain and a beta-2 microglobulin MHC Class I molecules, IgG IgM/IgG interaction with cell membranes or the extracellular matrix leads to Ab-mediated cytotoxicity Antibody-mediated, Anaphylaxis is a life-threatening reaction induced by Type I hypersensitivity, Vasculitis is a symptom of IgG-mediated hypersensitivity IgG, MHC Molecule MHC class II molecules are MHC molecules found on the surface of antigen-presenting cells MHC Class II molecules, Antibody-mediated The following forms of hypersensitivity are antibody-mediated Type I hypersensitivity, MHC Class I molecules MHC class I molecules present peptide antigens to T-cytotoxic cells T-cytotoxic cells (CTLs), Type III hypersensitivity circulating Ab-Ag complexes leads to localized abscesses or necrotizing vasculitis Vasculitis, MHC Molecule Central tolerance in the thymus involves the positive and negative selection of immature T-cells based on how well they recognize and bind to MHC molecules Central Tolerance, diffuse erythematous macules seen in the image are indicative of a Rash, Type II hypersensitivity is mediated by the antibodies IgG, Cyclosporine Cyclosporine, Basiliximab, and a corticosteroid are administered to prevent transplant rejection Corticosteroids, Complement can play a significant role in autoimmunity, such as ANCA-associated vasculitis Vasculitis, Bradykinin Bradykinin increases vascular permeability and vasodilation, which is implicated in anaphylaxis Anaphylaxis, Complement complement activated in both Type II and III hypersensitivity as part of the immune response, causing unintentional tissue damage Type II hypersensitivity, Thymus central tolerance involving immature T-cells occurs in the cortex and medulla of the thymus Central Tolerance