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This Concept Map, created with IHMC CmapTools, has information related to: A5 Hershel Greene, D-dimer test Specific test used to determine the amount of fibrinolysis Fibrin, EKG this test is useful for monitoring artial fibrillation Warfarin, von Willebrand factor Binds subendothelial collagen in response to Vascular Injury, Myocardial Infarction is measured dianostically through electrodes EKG, Thrombosis can be confirmed with this test including DVT D-dimer test, von Willebrand factor stabilizes factor VIII in Intrinsic pathway, Myocardial Infarction in this condition, this is activated via tPA which is used to prevent clot formation Plasminogen, Pulmonary embolism Presents with Fatigue, PF4 Complexes with Heparin, Chest X ray Useful in ruling out other conditions that might present similarly to Pulmonary embolism, Hematocrit has a direct relationship with Hemoglobin, IgG complexes of PF4-heparin suggest HIT PF4, Fibrin Stabilizes clot in as a product of secondary hemostasis Platelets, Hershel Greene - right leg pupura - hypotensive, tachycardic - T3-5 boggy, erythematous (PE suggestive) - D-dimer negative, 4T score: 7 - H&H low, thrombocytopenic - SRA positive, PF4 positive Highly sensitive and specific test for diagnosing HIT can help differentiate different HIT from other causes of Thrombocytopenia Serotonin Release Assay, Extrinsic pathway combine with in the coagulation cascade Common Pathway, Platelets irreversible competitively binds TXA2 receptors on platelets Aspirin, Fibrinogen Not accurately measured by D-dimer test, Aspirin Irreversible COX1 inhibitor used to reduce the risk of Thrombosis, Extrinsic pathway combine with in the coagulation cascade Intrinsic pathway, Plasmin Degrades clotting factors such as Fibrinogen