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This Concept Map, created with IHMC CmapTools, has information related to: Hypertension, respiratory acidosis acts on Kidney, Liver etc. breaks down RBC, Low cardiac output link Hypertension, Disease affects Kidney, cholesterol contribute plaques, Hypoxia acts on Kidney, Hypoxia ???? respiratory acidosis, Liver etc. breaks down bilirubin, Thalassemia alpha or beta Major, intermedia or Minor small or mis-shaped RBC, Exercise may reduce sympathoadrenergic activity, calcium causes contraction constrict vessels, Hypoxia stimulation peripheral chemoreceptors, narrowing of vessels results in Hypertension, Vitamin B6, B9, B12 used by Bone marrow, Digestive System reduced levels Selenium, Iodine, Iron. Copper etc., Pernicious anaemia reduces levels Vitamin B6, B9, B12, apoptosis maturing nucleated erythroid cells Bone marrow, Angiotensin II biosynthesis aldosterone, Hypertension increase pressure on juxtaglomerular cells Kidney, ARB inhibitors = Candesartan raise K & Renin? Na + K levels + blood volume