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This Concept Map, created with IHMC CmapTools, has information related to: C-1, Hallucinations Psych ROS Auditory, 5-HT2A receptor Usage of atypical antipsychotics decreases the amount of extrapyarmidal symptoms; is used in the treatment of bipolar disorder Extrapyramidal symptoms, DSM Pt symptoms relevant to creating a differential diagnosis Appears easily agitated, threatens staff, Jack Dawson 25 Y/O Male C.C. "Police picked me up for some reason. Probably been told to stop me", Positive symptoms Are caused by Dopamine hyperactivity in the mesolimbic pathway Mesolimbic pathway, Prolactin Prolactinoma is a result of D2 blockade which results in increase prolactin levels and infertility issues Dopamine, Urine Drug Screen tests positive for PCP PCP, Hyperthyroidism Overactive thyroid that produces and exces of thyroid hormones may lead to symptoms that resemble schizophrenia Schizophrenia, Pyschotic episode Symptoms of a psychotic episode include agitation and aggression both of which present a danger to the patient and others Appears easily agitated, threatens staff, Nigrostriatal pathway Blockade of D2 receptors in the Nigrostriatal pathway results in EPS and Parkinsonism Parkinsonism, Myxedema Myxedema is a condition associated with severe hypothyroidism, another symptom of which is a compensatory increase in Thyroid Stimulating Hormone Thyroid Stimulating Hormone, Schizophrenia Defined by the DSM-V as a chronic mental illness with positive symptoms, negative symptoms, and cognitive impairment DSM, Auditory These are all positive symptoms Positive symptoms, Glutamate Excitatory neurotransmitter that binds to NMDA receptors in the brain NMDA receptor, D2 receptor Blockade of D2 receptors outside of the mesolimbic pathway leads to significant negative effects Nigrostriatal pathway, "Police picked me up for some reason. Probably been told to stop me" Pt symptoms relevant to creating a differential diagnosis Hallucinations, Dopamine release of dopamine regulates prolactin release in tuberoinfundibular pathway Tuberoinfundibular pathway, 5-HT2A receptor Is a G protein-coupled receptor G protein-coupled receptor, DSM Pt symptoms relevant to creating a differential diagnosis Delusions, PCP PCP prevents Glutamate's excitatory function by blocking its action on NMDA receptors Glutamate