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This Concept Map, created with IHMC CmapTools, has information related to: C-1 Case 7 Hershel Greene, Hershel Greene 65 Y/O M C/C "Sudden Chest Pain" Presents with Current Medications, Heparin ???? PF4, Platelets Pt's low platelet count (90,000) indicates thrombocytopenia. PT/PTT would still be unchanged due to no affect on coagulation PTT, PF4 ELISA Detects ABs against IgG, Platelets ???? PF4, Hershel Greene 65 Y/O M C/C "Sudden Chest Pain" Presents with Sharp CP worse with inspiration, Vit K Synthesis of Factor VII is dependent on Vitamin K Factor VII, Dyspnea, Anxiety, Chest pain, Tachycardia, Hypotension, 91% POX Past MHx Knee replacement surgery eight days prior, Dyspnea, Anxiety, Chest pain, Tachycardia, Hypotension, 91% POX Social Hx Mother died at 80 y.o. of multiple myeloma, Vascular Injury will damage endothelium layer of vessel Endothelium, Serotonin release assay Serotonin release assay can be used to detect Heparin-induced thrombocytopenia if platelets activate in response to heparin Heparin, Factor VII The extrinsic pathway consists of FVII and III and is activated secondary endothelial (external) damage Extrinsic pathway, Endothelium will release tissue factor when damaged Tissue factor, Dyspnea, Anxiety, Chest pain, Tachycardia, Hypotension, 91% POX Social Hx Pt's father "complained of same type of feeling when I brought him to the hospital years ago. He died several days later", Hershel Greene 65 Y/O M C/C "Sudden Chest Pain" Presents with Dyspnea, Anxiety, Chest pain, Tachycardia, Hypotension, 91% POX, Platelets Activated platelets release serotonin which can be detected on a serotonin release assay Serotonin release assay, Current Medications 81 mg QD Aspirin, Current Medications 40 mg BID Enoxaparin is a LMWH Heparin, Dyspnea, Anxiety, Chest pain, Tachycardia, Hypotension, 91% POX Past MHx HTN+, Acid Reflux, EKG EKG can diagnose Myocardial Infarctions by detecting changes in EKG tracing due to cardiac muscle damage that occurs during an MI Myocardial infarction